Trauma, for the most part, is just a device to humanize the characters.
DC did do a run of "One Bad Day" for the bat-baddies that was supposed to be villain-triggering moment/origin story, but sometimes they don't want to cure cancer, they just want to turn people into dinosaurs.
Edit: threw up a convo from Soule's Shulk run with Shocker I liked about "wanting to be more" and the hero/villain breakdown
Edit2: Ow, the text was blurrier than I thought after uploading it. Pertinent parts:
Shulk: If I remember right, you built these things [his gauntlets]. You know, I couldn't build anything like these. I just don't get you guys sometimes. If you can do this, you don't have to do what you do. You could be so much more.
Shocker: You know, I look at you, you spent all that time, all that dough to become a lawyer... I mean, hell. I look at you and think... Wow, she could be so much more. Now, can I please have my damn gauntlets back?