I would also love to know if you can run apps like MS company portal, or other "jail" like applications?
Short answer: No. It's more prudent to get a separate phone for work (or ask the company to buy you one) instead of trying to circumvent policies which /e/OS cannot normally pass. Some states have laws requiring employers to reimburse you if you need to use personal devices for work.
Longer answer for curiosity:
It is technically possible, but can only be done via leaked keys with questionable legality and thus unlikely to be incorporated by /e/OS officially. Google has rolled out hardware-based attestation where each device has a non-extractable key which can sign a message that attests that the device is locked and running a certain firmware version.
As usual with Android OEM security, a large amount of keys have been leaked enabling this attestation to be spoofed. Google has been revoking the leaked keys yet new ones keep appearing in the wild. The experience is even worse if you have a cheap Android phone with one of the revoked keys - Imagine suddenly being unable to log in to your banking app because your otherwise-normal phone no longer passes an "integrity check" through no fault of your own. The keyword is "keybox" if you want to dig deeper into this disaster.
In any case, I strongly advise that you not do this to access corporate resources - Standing up against big tech and maximizing digital privacy is one thing, but it's another matter when it has to do with your livelihood. Pick your battles.
