Amoebas eat man alive over months in puzzling, ultra-rare cautionary tale

Fatesrider

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So, they put him on immunosuppressant drugs. But his condition only worsened, and the lesions only progressed.
And that's what probably killed him. His own immune system was shut down by the drugs, and the bug had a less hostile environment in which to thrive.

The images are about a 5/10 on the ick scale, too. If you're squeamish, don't look.
 
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FranzJoseph

Ars Centurion
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(A graphic image of his case is here, but be warned.)
Unlike the flesh‑eating V. vulnificus bacteria Dr. Beth previous article's photos rated at around 2.3 Beths , this one's photos rate around 7 Beths for me, so be really warned before clicking the image link. And just for reference, I've seen lots of quite gruesome injuries myself over the years…

ETA: More like 5 Beths on the gruesome scale at first, but imagining the fate of the poor patient long‑term puts it up to 7 for me.
 
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And that's what probably killed him. His own immune system was shut down by the drugs, and the bug had a less hostile environment in which to thrive.

The images are about a 5/10 on the ick scale, too. If you're squeamish, don't look.

OMG, what's a 10 ?

The guy with ALIVE with that !
 
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Guess it's time to have a convo with the wife - she regularly does nasal rinses with tap water....
I broke myself of that habit when amoebas in the city water got a woman in Seattle. It's perfectly safe to drink, but they make no guarantees when it comes to putting it up your nose. Saline spray bottles from the drug store are cheap and convenient.
 
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Before my time, we had a close family acquaintance die from amoebic encephalitis many decades ago, before any treatments (or even just proper diagnostic practices) were available there back then. Possibly a Naegleria fowleri case, although we won't ever know.

It wasn't pretty. At the very least they were in a coma for the last few weeks of their life support. From what I heard, they went from a relatively cognitive state to an outright coma during the course of just a few days…

Watch your amoebas, people, and don't ever bath in the same pool as RFK jr. does!

IIRC there was a particularly bad Naegleria fowleri local outbreak in the 1970s (?) in one European country with around 20 kids catching it in a swimming pool during their sport training. Turned out much later that even though the water was chlorinated, there were some still pockets of water inside bad tile cladding where the chlorine didn't reach. 16 kids died.

For some good news, several novel organo‑boron (!!!) compound anti‑protozoals seem to show pretty good efficacy against many parasitic amoebas including sleeping sickness and N. Fowleri, at least in mice trials so far (survival rate from 1% to 28% in mice is pretty big IMO). And another drug just I can't remember the name of IIRC passed phase 1 or 2 for human trials against sleeping sickness, which would be a great fucking thing, as that disease is quite endemic in Africa.
 
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Unlike the flesh‑eating V. vulnificus bacteria Dr. Beth previous article's photos rated at around 2.3 Beths , this one's photos rate around 7 Beths for me, so be really warned before clicking the image link. And just for reference, I've seen lots of quite gruesome injuries myself over the years…

ETA: More like 5 Beths on the gruesome scale at first, but imagining the fate of the poor patient long‑term puts it up to 7 for me.
Can you provide a conversion factor from Beths to the 10-point Rat Lungworm Scale?¹

__________
¹i.e., rat lungworm itself = 10RLS.
 
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OMG, what's a 10 ?

The guy with ALIVE with that !

Well, if she ever does an article about the narcotic "krokodil," my guess is that'd be pretty close. Nothing like pictures of people who are addicted to a drug that literally eats their face, yet continue injecting it. It's like leprosy, but self inflicted.
 
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I broke myself of that habit when amoebas in the city water got a woman in Seattle. It's perfectly safe to drink, but they make no guarantees when it comes to putting it up your nose. Saline spray bottles from the drug store are cheap and convenient.
Or just let it run a bit off the tap and then boil it, that will kill all the bugs including Legionella possibly lurking in your pipes or boiler heater. As for saline, it's pretty easy to add salts for proper osmolality. At least here where I live the tap water is generally really safe (and often better quality than bottled), it's just when people store it for a long time in a boiler at lower than 55°C or so where Legionella develops.
 
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Or just let it run a bit off the tap and then boil it, that will kill all the bugs including Legionella possibly lurking in your pipes or boiler heater. As for saline, it's pretty easy to add salts for proper osmolality. At least here where I live the tap water is generally really safe (and often better quality than bottled), it's just when people store it for a long time in a boiler at lower than 55°C or so where Legionella develops.
I think Seattle's water is perfectly safe. For its intended purposes. When people go off-label, they assume risks. In other words, don't go putting your tap water up your nose either.
 
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Every time I read about something like this happening, I just think, why can’t it happen to RFK Jr for once?
Who says it hadn't? The current admin certainly looks like being headed by a brain parasite. Wasn't there a Pohl novel with brain slugs living on peoples' heads or something like that? Orange ones I guess…

Or his diet of raccoon penises really works for him ;-)

/s
 
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poltroon

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I'm curious as to why the exposure to the red tides and hurricane waters was discounted as a cause/source.
The Yale doctors noted that the lesions began after he returned from Florida, where he spent the winters. While there, he was exposed to a red tide (caused by algae) while cleaning up after a hurricane.
That seems a very obvious potential source, or perhaps a co-infection factor that allowed the amoebas to thrive on his legs.
 
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MedicalGeek

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I broke myself of that habit when amoebas in the city water got a woman in Seattle. It's perfectly safe to drink, but they make no guarantees when it comes to putting it up your nose. Saline spray bottles from the drug store are cheap and convenient.
And all made in the developing world by companies with probably poor sterility standards. Boil your own water use immediately as soon as it cools that’s a better option
 
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I broke myself of that habit when amoebas in the city water got a woman in Seattle. It's perfectly safe to drink, but they make no guarantees when it comes to putting it up your nose. Saline spray bottles from the drug store are cheap and convenient.
I have a Navage at the behest of my mother. After the stories Dr Mole has posted, I am diligent in using distilled water and always using saline with it. I'm not too terrified of death in general, but slowly dying to amoebas is not how I want to go out.
 
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I have a Navage at the behest of my mother. After the stories Dr Mole has posted, I am diligent in using distilled water and always using saline with it. I'm not too terrified of death in general, but slowly dying to amoebas is not how I want to go out.
I never met the guy they hired to replace me when I left one job, but within a year or so he was killed by flesh-eating bacteria. It doesn't make any logical sense whatsoever but on some gut level it feels like I dodged a bullet.
 
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