CDC study finds big declines in hospitalizations—and they may be underestimates.
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Baby hospitalizations from RSV fell up to 71% with new vaccine, treatment
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I'm imagining the CDC scientists quickly hiding their work under a blanket every time RFK Jr. walks by.
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Lots of development work has always been done in the EU. And the EU just started a major program to get US scientists to the EU, so all the US top scientists interested in science will leave soon.
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I agree fully with the suggestion to track down an aggressive forward looking doc with ID/Immunology/pulmonary credentials to get your child one of the vaccines early in the respiratory virus season as a trial. Although you note in later comments that it cannot be gotten I suspect that this is a personal thing with that doc. His/her choice of course.
However I take issue with the assertion that there is nothing magic about the immune system in pregnancy. The fact that the mom does not reject the fetus, even if there is a large maternal/paternal haplotype difference is in and of itself magical and relates to a major change in the adaptive and intrinsic immune system.
Eg There is some worry about pregnancy in SLE patients (an autoimmune dysfunction illness) although our ability to handle that has improved substantially in recent years. (Some disagree- I'm on the it is "more likely to flare" side) Hydroxychloroquine partially for the win. Just had to mention a real use for that drug.
disclaimer: I did rheum and used off label meds, complicated, dangerous ones, by the kilo during my years.
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My wife just took the maternal vaccine at week 34. I live in a country that lags behind the West by a little bit: the vaccine was just approved for use. I feel quite fortunate that she was able to receive it. I (not a typical candidate as I’m an adult male) also took the vaccine in order to try to foster a little herd immunity within my household.
Some notes for people interested in the RSV vaccine:
- There is now a Guillain-Barré warning attached to the vaccines. I forget the exact number but there was something like 9 excess cases per million doses (or something like that). There is a CDC or FDA slide deck floating around that details this. So, if you’re like me, and not generally a candidate - consider this risk. For soon-to-be-mothers and the elderly, the benefit greatly outweighs the risk.
- There was a slight increase in the rate of preterm birth amongst pregnant women during clinical trials. Again, forgetting the exact number, but I believe it was a ~1% increase from like 4.5% to 5.5%. When the week of gestation for vaccine administration was restricted to 32 weeks minimum, this increase disappeared. Thus the current recommendation for 32 to 36 weeks for receiving it.
EDIT: When I say “vaccines” I’m referring to Abyrso (Pfizer) and Arexvy (GSK); not the monoclonal antibody version.
EDIT 2: Here is the slide deck that I referenced re: GBS. https://www.cdc.gov/acip/downloads/slides-2024-06-26-28/06-RSV-Adult-Lloyd-508.pdf
Some notes for people interested in the RSV vaccine:
- There is now a Guillain-Barré warning attached to the vaccines. I forget the exact number but there was something like 9 excess cases per million doses (or something like that). There is a CDC or FDA slide deck floating around that details this. So, if you’re like me, and not generally a candidate - consider this risk. For soon-to-be-mothers and the elderly, the benefit greatly outweighs the risk.
- There was a slight increase in the rate of preterm birth amongst pregnant women during clinical trials. Again, forgetting the exact number, but I believe it was a ~1% increase from like 4.5% to 5.5%. When the week of gestation for vaccine administration was restricted to 32 weeks minimum, this increase disappeared. Thus the current recommendation for 32 to 36 weeks for receiving it.
EDIT: When I say “vaccines” I’m referring to Abyrso (Pfizer) and Arexvy (GSK); not the monoclonal antibody version.
EDIT 2: Here is the slide deck that I referenced re: GBS. https://www.cdc.gov/acip/downloads/slides-2024-06-26-28/06-RSV-Adult-Lloyd-508.pdf
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USA motto should be: "Vaccine baby, Vaccine!"
Even "This is science, bitch!"
And then impeach the giant orange cry baby and its gang.
Even "This is science, bitch!"
And then impeach the giant orange cry baby and its gang.
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The problem with GBS and vaccines is that the excess rate of GBS is tiny. Small enough to have a hard time showing statistical significance. One of the COVID vaccines that showed a statistically significant increase in GBS, even, was because the control group had a lower than normal rate for GBS than expected across a large population, while the vaccine group had a normal rate for GBS. That could be because the GBS rate was down that year compared to normal, due to all the social distancing. But it could also just be indicative of statistical noise.
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CDC discusses exactly that in the post-licensure safety data section of this page:
https://www.cdc.gov/vaccine-safety/vaccines/rsv.html
And here is the link to the warning issued by FDA:
https://www.fda.gov/vaccines-blood-...o-and?utm_medium=email&utm_source=govdelivery
The good news is neither my wife and I had GBS symptoms during our 42-day post-vaccination. It was worth it to protect our little girl.
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Measles for example don’t kill enough people to make republicans die out (fortunately). Covid wasnt enough for that.
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yes, the current Kennedy family scion will scotch this pretty quickly i'm sure. Don't want to have vaccines get a reputation for doing anyone any good. fortunately smallpox vaccine and disease far enough in the past to pretend it never happened.
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He already cancelled the meeting where they make decisions about the yearly flu vaccine. Its not news yet, but the flu vaccine has ALREADY been cancelled.
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A whole bunch of things are linked to dementia & Alzheimers Disease, high among them inflammation, lack of exercise, infections, and family history. AFAIAA, there are not any known correlations between specific infections and AD (or perhaps more accurately, just about everything correlates similarly).
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It won't be ending until RFK Jr and his patron depart the corridors of political power. I just hope the comment isn't prescient.
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A scarily large fraction of increased economic productivity over the last 150 years is due to improvements in sanitation and health.
We're going to be paying for this (mal)administration for a long time.
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The big things I've been reading recently seems to be a connection with mouth bacteria, and also sinus/nasal infections. Both for the same reason, those areas have direct connections to the brain and bypass the blood brain barrier.
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I honestly hadn't thought about that before directly but it seems obvious once it's stated.
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Like lightning rods after Ben Franklin, many churches refused them as 'thwarting God's will'. I'll leave the logic of that to the theologians. Fortunately, most of the actual theologians I've been acquainted with are fairly practical and sensible.
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Quite a few of us older folks who had inoculations in 1972 or later should be OK too. Many people who traveled to third-world countries after 1972 were also re-vaccinated for smallpox (e.g., I have two smallpox vaccination scars; the second vaccination I received before traveling to the middle-east in 1972).
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Not all of them, but certainly many are looking at their options, and I know of at least a few who are seriously considering it. And yes, the EU is looking to capitalize on the U.S.'s collective stupidity and is actively recruiting.
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The fact that the mom most often does not reject the fetus...
Unfortunately, Rh incompatibility and Coombs positivity are proof this is not always true. Fortunately, modern medicine has treatments that help. (And if a doctor tells you that you or your spouse can't be Coombs positive on a first pregnancy, you may want to talk to another doctor.)
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Yes your counterexamples are true but do not negate my original assertion.They do not prove that there is not something almost magical about the immune system in almost all pregnancies. Rh compatible children are not generally rejected. And Rh incompatible children get hemolysis not rejection as well. I am not in this field but are the switches that make mom and her Treg cells tolerate the fetus and then switch back postpartum understood??
The Rh incompatibility attack is specific to that pairing alone. The fetus gets hemolytic anemia not rejection like a transplanted kidney. The remaining portion of the mother's immune system does not get switched back to an anti fetal state. Strange is that not?? The Treg cells do not abrogate their general benefit to the child.
And please do not bring microchimerism and autoimmune states up. It is beyond this discussion.
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