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Which is why my last paragraph said "But even then, doubling the price of the higher estimate in the 2018 paper to account for additional cost would still result in insulin that is a fraction of the cost currently being charged by Eli Lily for its generic product." I'm agreeing that they can...

Let me preface this by saying that I am not trying to defend Eli Lily's current insulin pricing. What they're doing is utterly reprehensible and as someone with a rare disease for which some treatments are priced even more ridiculously high than insulin it infuriates me to no end that they are...

Seattle Children's Hospital has a COVID-19 vaccine clinic open to all ages. I just checked and they have plenty of openings over the next week or so. Scroll down to the "Scheduling Your Vaccine Appointment" section and select the location to find the registration links...

You're also not committing to buying gas at a set price at that station for a long period. It's much easier to shop around and take your business elsewhere if you think a station is overcharging.

I'm not following how it would reduce rent for all apartments, but if we continue with the job analogy this is really like declining lower paying job offers in the hopes of getting a bigger salary. While you're waiting for that better offer you're earning zero income while still having to pay...

I live on an area with looser zoning laws where at least half a dozen new apartment complexes have been built in the immediate area over past five years and a few properties have even expanded. The rent for my unit has continued to increase at the same rate annually with the exception of the...

After reading that, I'm wondering if an algorithm would explain one of the weirdest pricing structures I've seen for a rental. The leasing agent showed me a calendar with pricing that was varied depending on the day the lease started and could charge by a few hundred dollars depending on the...

I renewed my lease a few months ago and with a 20% increase I looked around in my area and found that my property had a unit that had been open so long that they were offering a one month discount on rent. I asked the property manager how they could justify raising the rent when they had a unit...

The US tried a version of that back in the spring. Lifting mask mandates for the vaccinated doesn't work if you have no enforcement mechanism and many states still don't have that.

Except that dexamethasone, an inexpensive anti-inflammatory steroid that's been around for decades, has been found to be useful in treating patients with severe COVID-19 in the later stages of illness. And it's well supported by research from many institutions. Big Pharma hasn't managed to...

I am loathe to agree with anything the NFL does, but I think they hit on a decent strategy here. https://www.nfl.com/news/nfl-covid-19-o ... elled-game

Not in the same way as a drug is. In that case, dose is more important because the drug is what's having a direct effect on the body and you need to keep enough in your system to make sure that it's effective but not enough that it's toxic. In the case of a vaccine, the antigen kick starts an...

I really wish the CDC had reported the risk of myocarditis from mRNA vaccines relative to the risk of myocarditis from COVID-19. We're all very likely to be exposed at some point in the future, the two options aren't vaccine or no vaccine, it's vaccine or COVID-19. From the CDC's numbers for the...

I wasn't told that I had the option of refusing HepB when they checked my titers and said that I needed another round, but I asked what would happen if I did and I'd just get furloughed without pay. However, if anyone who works in the hospital that the research institute is attached to refused...

It seems they thought the honor system was actually worth something. Instead masking has become even more politicized than it was before.

The fragments of the platelets left over after they're destroyed retain some clotting activity, enough that what's left of them starts sticking together in an uncontrolled way in various blood vessels. There's another type of clotting disorder where an overabundance of platelets respond to...

You know what would make this paper stronger? Using a relevant cell line for the infectivity assay. I get that nearly every lab has Vero cells hanging around, but those monkey kidney cells gave us some extremely bad data when testing the antiviral activity of hydroxychloroquine that we're still...

Moderna and Pfizer both used saline placebos in their control arms, but AstraZeneca used a dose of the meningococcal ACWY vaccine as a control. The thinking goes that some of the the immune response to a vaccine is general and not specifically targeted to whatever is in the vaccine, so getting...

It depends on the industry. In biotech, patent lawyers are more or less required to have a PhD in that field as well as a law degree. Maybe we just need to send them back to school.

If Charles Carreon was perturbed by the internet's response to him essentially extorting $20k from a webcomic, then he is going to be positive apopleptic when the internet is done with him for this stunt.